Sitemap

A list of all the posts and pages found on the site. For you robots out there is an XML version available for digesting as well.

Posts

Future Blog Post

less than 1 minute read

Published: January 01, 2199

This post will show up by default. To disable scheduling of future posts, edit config.yml and set future: false.

Blog Post number 4

less than 1 minute read

Published: August 14, 2015

This is a sample blog post. Lorem ipsum I can’t remember the rest of lorem ipsum and don’t have an internet connection right now. Testing testing testing this blog post. Blog posts are cool.

Blog Post number 3

less than 1 minute read

Published: August 14, 2014

This is a sample blog post. Lorem ipsum I can’t remember the rest of lorem ipsum and don’t have an internet connection right now. Testing testing testing this blog post. Blog posts are cool.

Blog Post number 2

less than 1 minute read

Published: August 14, 2013

This is a sample blog post. Lorem ipsum I can’t remember the rest of lorem ipsum and don’t have an internet connection right now. Testing testing testing this blog post. Blog posts are cool.

Blog Post number 1

less than 1 minute read

Published: August 14, 2012

This is a sample blog post. Lorem ipsum I can’t remember the rest of lorem ipsum and don’t have an internet connection right now. Testing testing testing this blog post. Blog posts are cool.

portfolio

Portfolio item number 1

Short description of portfolio item number 1

Portfolio item number 2

Short description of portfolio item number 2

publications

Temperature-dependent influence of FliA overexpression on PHL628 E. coli biofilm growth and composition

Published in Frontiers in Cellular and Infection Microbiology, 2021

It was demonstrated by Prof. Jiajia Ma’s group at Shanghai Tong University that an arene reduction reaction by hydrogen atom transfer enabled by energy transfer catalysis allows for a higher functional group tolerance. My goal was to support the hypothesis that the chemoselectivity of the reaction was dictated by triplet energies rather than reduction potentials in contrast to conventional reduction reactions. I was able to accomplish this through calculations of triplet energies and dexter energy transfers from an iridium-based photosensitizer, showing that a photocatalytic pathway prevents the functional groups from getting activated while allowing the hydrogen atom transfer to take place. In addition, I was able to propose a mechanism for this photocatalytic hydrogen atom transfer reaction through various Gibbs free energy and minimum energy crossing point calculations. Specifically, I calculated the energy barriers for all theoretically possible 48 reaction pathways, allowing me to elucidate the structural configurations that allow for a smooth hydrogen atom transfer reaction. This research paper in which I am the first author along with the principal experimentalist is published in Angewandte Chemie.

Recommended citation: Buck, L.D. ‡, Paladino, M.M. ‡, Nagashima, K., Holtzman, J.S., Brezel, E.R., Urso, S.J., Ryno, L.M. Temperature-dependent influence of FliA overexpression on PHL628 E. coli biofilm growth and composition. Frontiers in Cellular and Infection Microbiology, 2021, 11, 775270. DOI: 10.3389/fcimb.2021.775270
Download Paper

Arene Reduction by Energy Transfer Catalysis Enabled Hydrogen Atom Transfer: Advancing the Chemoselectivity

Published in Angewandte Chemie International Edition, 2023

This paper is about the number 1. The number 2 is left for future work.

Recommended citation: Liu, D.‡, Nagashima, K.‡, Liang, H., Yue, X., Chu, Y., Chen, S., Ma, J. Arene Reduction by Energy Transfer Catalysis Enabled Hydrogen Atom Transfer: Advancing the Chemoselectivity. Angew. Chem., Int. Ed, 2023. DOI: 10.1002/anie.202312203
Download Paper

Kyogo Nagashima

Sitemap

Pages

Posts

portfolio

publications

talks

teaching